Expresión de búsqueda: PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13 
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Descriptor Inglés:   Protein Tyrosine Phosphatase, Non-Receptor Type 13 
Descriptor Español:   Proteína Tirosina Fosfatasa no Receptora Tipo 13 
Descriptor Portugués:   Proteína Tirosina Fosfatase não Receptora Tipo 13 
Categoría:   D08.811.277.352.650.775.300.860
D12.644.360.585.860
D12.776.476.564.860
Definición Inglés:   A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing five different PDZ domains, and a carboxyl-terminal phosphatase domain. In addition to playing a role as a regulator of the FAS RECEPTOR activity this subtype interacts via its PDZ and FERM domains with a variety of INTRACELLULAR SIGNALING PROTEINS and CYTOSKELETAL PROTEINS. 
Nota Histórica Inglés:   2008(2001) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   52702 
Identificador Único:   D054595 

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